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Κυριακή 26 Ιουλίου 2015

How Apple’s ResearchKit Is Changing The Pharmaceutical Industry




When Apple announced, last year, that it was developing a watch that had the functions of a medical device, it became clear that the company was eyeing the $3 trillion health care industry; that the tech industry sees medicine as the next frontier for exponential growth.
Apple’s recent announcement of ResearchKit shows that it has an even greater ambition: It wants to also transform the pharmaceutical industry by changing the way clinical trials are done.
ResearchKit is a platform that will let app builders capture and upload data from patients who have a particular disease. Our smartphones already monitor our activity levels, lifestyles and habits. They know where we go, how fast we move, and when we sleep. Some smartphone apps already try to judge our emotions and health based on this information; to be sure, they can ask us questions.
ResearchKit apps will enable constant monitoring of symptoms and of reactions to medications. Today, clinical trials are done on a relatively small number of patients, and pharmaceutical companies sometimes choose to ignore information that does not suit them. Data that our devices gather will be used to accurately analyse what medications patients have taken, in order to determine which of them truly had a positive effect; which simply created adverse reactions and new ailments; and which did both.

The best part is that the clinical trials will be continuing — they won’t stop once the medicines are approved by the FDA.
Apple has already developed five apps that target the most prevalent health concerns: diabetes, asthma, Parkinson’s disease, cardiovascular disease, and breast cancer. The Parkinson’s app can, for example, measure hand tremors, through an iPhone touchscreen; vocal trembling, using the microphone; and gait, as you walk with the device.
Combined with genomics data that are becoming available as plunging DNA-sequencing costs approach the costs of regular medical tests, a health-care revolution is in the works. By understanding the correlations between genome, habits, and disease — as the new devices will facilitate — we will get closer and closer to an era of Precision Medicine — in which disease prevention and treatment is done on the basis of people’s genes, environments, and lifestyles.






Google and Amazon are one step ahead of Apple in the data they capture — they offer a repository for DNA information. Google also announced last year that it is developing a contact lens that can measure glucose levels in a person’s tears and transmit these data via an antenna thinner than a human hair. It is developing nanoparticles that combine a magnetic material with antibodies or proteins that can attach to and detect cancers and other molecules inside the body and notify a wearable computer on the wrist. And it wants to control ageing.
In 2013, Google made a significant investment in a company called Calico, to research diseases that afflict the elderly, such as neurodegeneration and cancer. Its goal is to understand ageing and, ultimately, extend life. It is also learning how the human brain works. One of its chief scientists, Ray Kurzweil, is bringing to life the theory of intelligence expounded in his book How to Create a Mind. He wants to enhance our intelligence with technology and allow us to back up our brains onto the cloud.
We may have been disappointed with the advances in medicine in the past because things have moved slowly because of the nature of the health care system itself. It hasn’t been focused on delivering health care — it has been about sick care. That’s because doctors, hospitals, and pharmaceutical companies only make money when we are in bad health; they don’t get rewarded for keeping us healthy. The good news is that the technology industry is about to change all this.