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Pfizer's billion-dollar Celebrex patent loss has Mylan, Actavis revving up generics

One of Pfizer's  top-selling products is suddenly vulnerable to generic competition 18 months earlier than expected. A U.S. court nixed a key Celebrex patent, putting the pain drug up for a sales fight in May. And generics makers Mylan and Actavis  are promising to launch their versions as soon as Pfizer's monopoly expires.

Pfizer will appeal, but barring success in a higher court, the company stands to lose billions in sales; Celebrex (celecoxib) brought in $2.9 billion in net sales last year, $1.9 billion in the U.S. Morningstar analyst Damien Conover says the ruling could cost Pfizer $1 billion this year and $2 billion next. And Mark Schoenebaum, an ISI Group analyst, figures Celebrex generics could lop 12 cents off Pfizer's 2014 earnings per share, if they make their debut in May.

Roche and Bayer expand their partnership into multiple projects

Ventana Medical Systems, Inc. (Ventana), a member of the Roche Group, announced that it has entered into a multi-year agreement with Bayer Pharma AG (Bayer) to develop companion diagnostics, with a focus on immunohistochemistry (IHC), across Bayer's portfolio of targeted therapy projects. This new agreement extends an already existing collaboration and focuses on the development of diagnostic tests for Bayer's biomarker targeted therapeutics from early discovery through commercialization.

Branded pharma revenues to rise 2%-3% in 2014, says Fitch

Revenues for brand-name drugmakers will rise just 2%-3% in 2014, forecasts ratings agency Fitch, but it adds that global pharmaceuticals is still one of its highest-rated industries, and that the sector outlook remains “stable.” 

 Moderate pressure from patent expiries, cost-containment policies in the European Union (EU) and weak employment in the US will be only partly offset by uptake of new products and strong growth in emerging markets, it says in a new report, which expects no significant divergence in the trend in profitability between US and EU-based drugmakers next year.

Fitch also believes that industry will find patent expiry levels in 2014 to be “manageable.” Patents on roughly $34 billion-worth of branded drug sales are set to expire during the year - accounting for approximately 3.6% of global market sales - compared to $28 billion this year and $55 billion in 2012.

Marketer of the Year Awards

Shire and Lundbeck have claimed the top title of marketing companies of the year in the prestigious PharmaTimes Marketer of the Year competition, the results of which were announced in London.

Lundbeck was named UK Marketing Company of the Year and Shire, International Marketing Company of the Year. This is the third year in a row that Shire has won the company title. Shire was also successful in other categories, scooping Marketing Team of the Year (Martin Smith, Lindsay Burbidge, Craig Dimblebee, Richard Knight and Louise Finke), while Eva Panarese was named International Marketer of the Year. Meanwhile, Lundbeck took home other wins – New Marketer of the Year went to Andrew Jackson, and Lance Boyd-Clark was awarded Aspiring Marketing Manager of the Year.

TOUGH TIME FOR BIG PHARMA

Global pharmaceutical industry is facing an unprecedented crisis in terms of sales growth, profitability and discovery of new drugs for the last some years now. With increasing rate of patent expiry of several blockbusters and reduced spending on research, top multinational drug companies are facing a rather gloomy future in the years to come. The Pharmabiz study of financial performances of 15 top international pharmaceutical companies during 2013 has revealed this prospects somewhat clearly.

The study shows that net sales of these 15 companies from the pharmaceutical segment including vaccines and generics during 2013, remained flat at $431 billion as against $430 billion reported in the previous year.

The top 10 pharma companies by 2013 revenue

FiercePharma | Eric Palmer

 

The earnings reports for the biggest of Big Pharma are all in. Bayer reported last week, making it possible to see how they stacked up as they came into the new year. There are no big surprises. Pfizer ($PFE) and Merck & Co. ($MRK), with ongoing patent issues and reorganizations, saw their positions fall a couple of notches, and AbbVie ($ABBV), having been spun off from Abbott Laboratories ($ABT) at the beginning of the year, didn't quite make the top 10. Its disappearance allowed Eli Lilly & Co. ($LLY) to make the list. It also helped Bayer HealthCare move up a couple of notches.

The ultimate guide for Pharma Marketing Champions

Το "Φαρμακευτικό μάρκετινγκ" αποτελεί αυστηρά εξειδικευμένο πεδίο εφαρμογής του μάρκετινγκ και χαρακτηρίζεται από πολλές ιδιαιτερότητες που κάνουν εξαιρετικά δύσκολη και δαπανηρή την υλοποίηση των ενεργειών του.

Το βιβλίο αυτό φιλοδοξεί να καλύψει το απόλυτο κενό σε ό,τι αφορά το πεδίο του φαρμακευτικού μάρκετινγκ στην ελληνική βιβλιογραφία. Στα περιεχόμενα ενσωματώθηκαν όλες οι βασικές και επίκαιρες γνώσεις γύρω από τη θεωρία, την πρακτική και τη δεοντολογία του μάρκετινγκ των φαρμακευτικών και των άλλων συναφών προϊόντων.

Ενδεικτικά στα περιεχόμενα του βιβλίου περιλαμβάνονται:
- Ανάλυση του περιβάλλοντος του "Φαρμακευτικού μάρκετινγκ"
- Ο σχεδιασμός της στρατηγικής μάρκετινγκ
- Η εφαρμογή του συστήματος Key Account Management από τις φαρμακευτικές εταιρίες.
- Η διαχείριση των κρίσεων στο φαρμακευτικό κλάδο
- Η Εταιρική Κοινωνική Ευθύνη και η Ηθική Συμπεριφορά των φαρμακευτικών εταιριών
- Οι στρατηγικές ανάπτυξης των φαρμακευτικών εταιριών
- Ο σχεδιασμός του προγράμματος μάρκετινγκ

Το βιβλίο εξυπηρετεί τις μαθησιακές και επαγγελματικές ανάγκες στελεχών επιχειρήσεων και οργανισμών που εργάζονται στον κλάδο των προϊόντων και υπηρεσιών υγείας και θέλουν να αποκτήσουν, να συστηματοποιήσουν η να εμπλουτίσουν τις γνώσεις που ήδη έχουν στο συγκεκριμένο πεδίο.

Το βιβλίο καλύπτει επίσης τις μαθησιακές ανάγκες προπτυχιακών και μεταπτυχιακών σπουδαστών των φαρμακευτικών σχολών καθώς και άλλων ΑΕΙ / ΤΕΙ και κολεγίων που υλοποιούν εκπαιδευτικά προγράμματα σχετικά με την οργάνωση και διοίκηση μονάδων υγείας.

Το πρώτο και μοναδικό βιβλίο στο είδος του στην Ελληνική γλώσσα

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Lilly, Pfizer and Merck slash doctor payments, but J&J and Forest shell out more

Some pharmaceutical companies have dramatically reduced payments to health professionals for promotional speeches amid heightened public scrutiny of such spending, a ProPublica analysis shows.

Eli Lilly & Co.'s payments to speakers dropped by 55 percent, from $47.9 million in 2011 to $21.6 million in 2012.

Pfizer's speaking payments fell 62 percent over the same period, from nearly $22 million to $8.3 million.

And Novartis, the largest drugmaker in the U.S. as measured by 2012 sales, spent 40 percent less on speakers that year than it did between October 2010 and September 2011, reducing payments from $24.8 million to $14.8 million.

The sharp declines coincide with increased attention from regulators, academic institutions and the public to pharmaceutical company marketing practices.

Pharma M&A activity rebounds in 2013

For an industry often characterized by its mega mergers of the late 2000s, it's no surprise that biopharma aggregate total M&A spend was in a six-year slump that reached a low point in 2012, according to figures released by Deloitte last year.

And in 2012, PriceWaterhouseCooper found deal spend was essentially flat (+1%). Now, a new PwC report shows that the downturn in spend may have been reversed in 2013.

According to data provided to PwC by Thomson Reuters, the pharmaceutical life science (PLS) industries (biotech, pharma, devices and diagnostics) saw deal value increase by $45 billion in 2013—a 45.8% increase from 2012.

The jump was helped by first-quarter deals like AbbVie's IPO and Pfizer's spin-off of its animal health segment, Zoetis. Pharma and life science IPOs overall were on the rise, too, with value up 11% and volume up 4% compared to 2012.

Two highlights from last year also propelled deal value: