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Τρίτη 21 Μαΐου 2013

Actavis to Buy Warner Chilcott in All-Stock Deal



The generic drug maker Actavis agreed on Monday to buy Warner Chilcott, a smaller rival, for about $5 billion in stock, in the latest flurry of deal-making in the specialty drug industry.

The merger comes after Actavis’s talks to sell itself to Valeant Pharmaceuticals fell through last month. After the failure of that proposed deal, Actavis turned to its talks with Warner Chilcott while turning down deal entreaties from bigger drug makers like Mylan, according to a person briefed on the matter.



Under the terms of the deal, the company will pay 0.16 of an Actavis share for each Warner Chilcott share. At Friday’s closing prices, that amounts to $20.08 a share, nearly 5 percent higher than Warner Chilcott’s closing price that day. Actavis will also assume Warner Chilcott’s $3.5 billion in long-term debt.

The combined company is expected to have about $11 billion in annual revenue, with focuses on products for women’s health, urology and dermatology. Actavis, itself the product of a merger of Watson Pharmaceuticals of the United States and Actavis of Switzerland, now specializes in generic drugs, including a version of Lipitor.

“We have set as our strategic corporate objective to build a leading global specialty pharmaceutical company,” Paul M. Bisaro, Actavis’s chief executive, said in a statement. “The combination of Actavis and Warner Chilcott creates a strong specialty brand portfolio focused in therapeutic categories with strong growth potential, and is supported by a deep pipeline of development programs.”

The merged company would be based in Ireland, Warner Chilcott’s current home, to take advantage of favorable tax laws in that country.

The deal requires the approval of shareholders in both companies, as well as the sanction of the Irish High Court.

The biggest shareholder of Warner Chilcott is Fidelity Management and Research, the mutual fund company, which held a 10 percent stake as of earlier this month, according to Bloomberg data. Fidelity Management is the second-largest shareholder of Actavis, with a stake of 5.7 percent, the data showed.

Actavis was advised by Bank of America Merrill Lynch and Greenhill & Company, while Warner Chilcott was advised by Deutsche Bank.

Top 10 Cardio Drugs 2012





For years, cardio was king. The world's all-time best-selling drug, Pfizer's Lipitor, after all, is an antihyperlipidemic drug. Cardio drugs have traditionally made up one of the largest categories of therapeutic treatment in the drug universe.
 
According to EvaluatePharma's World Preview 2018 report, combined sales of antihypertensive drugs and antihyperlipidemics were more than $70 billion in 2011. That would put them at the top of the heap. Sales of antihypertensive drugs alone were more than $40 billion that year, making them the second-largest therapy area defined by the report, behind oncology drugs at $64.4 billion. The list, compiled by EvaluatePharma, includes the theraputic areas categorized as cardio, so it does not include some products sometimes used for heart disease but not in that therapeutic area, including blood thinners like Plavix


But many of the top cardio drugs are long in the tooth, and generics are now eating their lunch. Did I mention Lipitor? Sales cratered last year, falling nearly 60%. Despite that, the drug placed third among the top 10 cardio drugs of 2012, a reminder of the stature it had achieved. Four of the top 10 have lost patent protection in the last two years, and most will be off patent by 2016, with only Merck's Vytorin protected until 2017.


Last year, the top 10 cardio drugs racked up sales of $28.644 billion, down 23% from the $37.271 billion they sold in 2011. Still, the group has made a lot of money for its companies for years and, in some cases, completely changed the treatment of heart disease.

It is an interesting list. Only Merck has two drugs in the top 10. The other drugmakers make up a broad swath of the pharma industry. Read our report below, and if you have some insights you would like to share, please do.




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